Proceedings of the International scientific and practical conference ―Science at the Frontier of Civilizations‖ (March 16-18, 2026) / Publisher website: www.naukainfo.com. – Helsinki, Finland, 2026. - 145 p.

51 The obtained results indicate that patients who had undergone radiotherapy demonstrated a greater degree of tooth loss and more complex dental arch defects from a clinical perspective. These findings are consistent with contemporary literature data showing that radiotherapy negatively affects the dentoalveolar system and is associated with a high prevalence of xerostomia and hyposalivation, more severe periodontal changes, and less favorable conditions for dental implant osseointegration with an increased risk of implant failure [1-5]. Therefore, patients with a history of cancer, particularly those who have received radiotherapy, require comprehensive dental evaluation, individualized pre-implant preparation, and careful assessment of periodontal tissue status when planning implant-supported rehabilitation. REFERENCES: 1. Abou-Bakr A, Ahmed E, William H, Hassanein FEA. Frequency of periodontal disease in head and neck cancer patients after radiation therapy: a cross- sectional study. BMC Oral Health. 2025;25(1):1008. doi:10.1186/s12903-025- 06391-7. 2. Abou-Bakr A, Hassanein FEA, William H, Ibrahim SS. Prevalence of late xerostomia and hyposalivation with associated risk factors in survivors of head and neck cancer after radiotherapy: a multi-centric cross-sectional study. Radiat Oncol. 2025;20(1):162. doi:10.1186/s13014-025-02737-1. 3. Fan S, Diaz L, Sáenz-Ravello G, Valmaseda-Castellon E, Al-Nawas B, Schiegnitz E. Comprehensive Update on Implants in Patients With Head and Neck Cancer (2021-2024): Systematic Review and Meta-Analysis of the Impact of Radiotherapy and Chemotherapy on Implant Survival. Clin Oral Implants Res. 2025;36(9):1035-1052. doi:10.1111/clr.14450. 4. Pacheco MCD, Prado AHR, Costa DV, Arantes LC, Portela CFT, Campos TPR, et al. Survival of dental implants in irradiated head and neck cancer patients