Proceedings of the International scientific and practical conference ―Current Issues in Science‖ (January 9-11, 2026) / Publisher website: www.naukainfo.com. – Dresden, Germany, 2026. – 179 p.

66 Practical advice: 1. In patients with nail psoriasis, it is advisable to routinely perform mycological examination using direct microscopy and/or culture testing to rule out onychomycosis. 2. Mandatory exclusion of fungal nail infection when prescribing systemic or biological therapy for psoriasis will help avoid complications, as immunosuppression can contribute to the progression of the infectious process. 3. Instrumental methods (dermatoscopy, ultrasound examination of the nail, capillaroscopy) should be used as a supplement to laboratory diagnostics, especially in complex or atypical clinical cases. 4. Biopsy of the nail apparatus should be considered as a backup diagnostic method in cases of resistant disease, questionable clinical situations, or suspicion of other pathology. 5. Primary care physicians and dermatologists are advised to increase clinical vigilance regarding the possible combined course of nail psoriasis and onychomycosis, which will reduce the number of diagnostic errors and prolongation of treatment. 6. From an organisational point of view, it is advisable to introduce standardised algorithms for the diagnosis of nail lesions in patients with psoriasis at the level of healthcare facilities. Conclusions. Nail psoriasis is a common manifestation of psoriasis associated with a more severe and prolonged course of the disease, reduced quality of life, and an increased risk of developing psoriatic arthritis. Frequent comorbidity with onychomycosis and the clinical similarity of their manifestations lead to a high risk of diagnostic errors and irrational treatment. In this context, timely mycological diagnosis and a systematic approach to the assessment of nail lesions, especially before prescribing systemic or biological therapy, are key to improving treatment efficacy and optimizing medical resources.