Proceedings of the International scientific and practical conference “Science in the Modern World” (January 19-21, 2026) / Publisher website: www.naukainfo.com. - Cambridge, United Kingdom, 2026. - 203 p.

105 UDC 612.821:612.44:591.111.1 Demchenko Olena Mykhailivna Doctor of Biological Sciences, Professor of the Department of Physiology Rodynska Galyna Oleksandrivna Candidate of Medical Sciences, Associate Professor of the Department of General Surgery, Surgery, Orthopedics and Traumatology of the Faculty of Postgraduate Education Demchenko Kseniia Oleksandrivna student Dnipro state medical university Dnipro city, Ukraine THE INFLUENCE OF THYROID HORMONES ON THE FORMATION OF DEFENSIVE SPATIAL MEMORY IN RATS UNDER EMOTIONAL LOAD DURING EARLY ONTOGENESIS Abstract. The study investigates the effects of thyroid hormones on the formation of defensive spatial memory in sexually immature rats under conditions of chronic and acute emotional load. It is shown that thyroid gland dysfunction modifies cognitive activity and anxiety levels, which determine the effectiveness of mnemonic processes during early ontogenesis. Keywords: thyroid hormones, thyroid gland, spatial memory, emotional load, anxiety, rats, early ontogenesis. Introduction. The influence of thyroid hormones on the development of the central nervous system is one of the key factors in the formation of cognitive functions during early