Proceedings of the International scientific and practical conference ―Science at the Frontier of Progress‖ (January 27-29, 2026) / Publisher website: www.naukainfo.com. – Paris, France, 2026. - 302 p.

113 MEDICAL SCIENCES AND PUBLIC HEALTH UDC 612.44:612.821:591.3 Demchenko Olena Mykhailivna Doctor of Biological Sciences, Professor of the Department of Physiology Rodynska Galyna Oleksandrivna Candidate of Medical Sciences, Associate Professor of the Department of General Surgery, Surgery, Orthopedics and Traumatology of the Faculty of Postgraduate Education Hrytsenko Anastasiia Oleksyivna student Dnipro state medical university Dnipro city, Ukraine THE ROLE OF THYROID HORMONES IN THE FORMATION OF ANXIETY IN RATS DURING EARLY ONTOGENESIS Introduction. Persistent psychoemotional stress is a characteristic feature of modern Ukrainian society. The psychoemotional state of the organism is determined by the coordinated activity of the nervous and humoral systems, particularly the hypothalamic–pituitary–thyroid axis, which plays a crucial role in adaptive regulation. However, data regarding the mechanisms underlying emotional behavior under conditions of thyroid dysfunction remain controversial. Therefore, the aim of this study was to investigate the neuromediator mechanisms involved in the