Proceedings of the International scientific and practical conference ―Oxford International Science Forum‖ (February 6-8, 2026) / Publisher website: www.naukainfo.com. - Oxford, United Kingdom, 2026. - 245 p.

191 To evaluate the impact of various tobacco and nicotine consumption modalities on peri-implant tissues, implant survival, and oral hygiene status, and to substantiate evidence-based preventive and clinical management strategies for implant patients who use nicotine-containing products. Materials and Methods. This extended abstract is based on an integrated analysis of original clinical data and peer-reviewed scientific publications published between 2020 and 2025. The analysis incorporates the author’s own clinical research evaluating oral hygiene indices (DI-S, CI-S, OHI-S, MGI, DMFT) among users of conventional cigarettes, heat-not-burn systems, and smokeless tobacco products. In addition, data from systematic reviews, meta-analyses, and observational studies addressing peri-implant inflammation, marginal bone loss (MBL), probing depth (PD), and implant failure rates in smokers and non-smokers were analyzed. Comparative assessment focused on identifying differentiated risk profiles associated with specific nicotine delivery methods and their relevance to implant therapy planning. Results. Clinical and analytical data demonstrate that conventional cigarette smoking is associated with the most pronounced negative impact on dental implant outcomes. Smokers exhibit significantly higher rates of early and late implant failure, increased probing depth, peri-implant inflammation, and marginal bone loss, frequently exceeding 2 mm during the first years of functional loading. Users of heat-not-burn systems and electronic cigarettes showed moderately reduced tissue destruction compared to traditional smokers; however, persistent peri- implant inflammation, delayed soft tissue healing, and increased biofilm accumulation were consistently observed. Smokeless tobacco users demonstrated localized gingival inflammation and mucosal changes at nicotine contact sites, which may indirectly compromise peri-implant tissue stability. Importantly, smoking cessation was associated with measurable clinical improvement. Studies indicate that discontinuation of nicotine use for at least 8–12