Proceedings of the International scientific and practical conference ―Paris Science and Education Forum‖ (March 2-4, 2026) / Publisher website: www.naukainfo.com. – Paris, France, 2026. - 293 p.

250 positive cells with minimal cytotoxicity and high chemical and physical stability [11, 13]. • Nanotechnologies in biopsy. The use of nanorobots, nanosensors, and micro- and nanoneedles allows tissue samples to be obtained with high precision and minimal trauma. Nanocoatings on instruments enhance durability and maneuverability. Additionally, nanotechnologies can be employed to label cells within samples, increasing the accuracy of histological verification [14]. • Nanosystems for drug delivery. Organic (liposomes, polymer-based nanoparticles, dendrimers) and inorganic (gold, carbon, mesoporous silica, magnetic, and quantum dots) nanoparticles and their hybrids provide targeted delivery of antitumor agents to TC cells. This approach reduces side effects, increases therapeutic efficacy, and allows integration of screening, diagnosis, and treatment into a unified system [15]. Thus, nanotechnologies significantly expand the capabilities for early diagnosis, biopsy accuracy, and personalized treatment of thyroid cancer (TC). Although most of these methods are still at the research stage, their integration into clinical practice promises substantial improvements in treatment outcomes and patients‘ quality of life. Early diagnosis and determination of the histological type of TC remain crucial for predicting disease progression and selecting the optimal therapeutic strategy. The use of molecular biomarkers in combination with contemporary techniques, such as polymerase chain reaction, genome sequencing, and mass spectrometry, enables precise verification of tumor cells, assessment of their aggressiveness, and formulation of personalized treatment approaches [11, 16]. The application of nanotechnologies in TC diagnostics opens new avenues for early detection and disease monitoring. Nanoparticles, nanosensors, nanorobots, and nanoscale drug delivery systems not only enhance the accuracy of examinations and biopsies but also enable effective targeted therapy with minimal side effects. The implementation of such technologies in clinical practice has the potential to significantly improve patient survival and post-treatment quality of life.

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