Proceedings of the International scientific and practical conference ―Science at the Frontier of Civilizations‖ (March 16-18, 2026) / Publisher website: www.naukainfo.com. – Helsinki, Finland, 2026. - 145 p.

54 the immunological resistance of insects and unfavorable conditions of detention [2, с. 11–12]. In this regard, there is growing interest in environmentally safe methods of prevention and treatment of infectious diseases in beekeeping. A promising direction is the use of probiotics, which contribute to the normalization of intestinal microflora, increase the body's natural resistance and improve the physiological state of bee colonies. [3, с. 40–41]. Along with this, antimicrobial agents are used in veterinary practice, in particular "Anolite", which is characterized by pronounced disinfectant activity and can be used to reduce the microbial load in bee colonies [4, с. 6-17]. The aim of the work is to scientifically substantiate the prospects for the combined use of the probiotic "Apinormin" and the product "Anolite" for the prevention and treatment of fungal diseases of honey bees. To achieve the goal, it was planned to analyze modern scientific sources on the use of probiotics in beekeeping, assess the possibility of using "Anolyte" in combination with probiotic cultures, and summarize experimental materials on the impact of combined feeding on the viability of insects and the level of their natural mortality [5, с. 72–73]. Analysis of modern scientific publications indicates a growing interest in the use of probiotics in the veterinary support system of beekeeping. Scientific works show that probiotic cultures contribute to the normalization of intestinal microflora, increase immunological resistance and positively affect the viability of insects [3, с. 42–43]. In particular, it has been found that the use of probiotic supplements helps increase the number of bacteria of the genus Lactobacillus in the intestine, which play an important role in maintaining microbiological balance and protecting the body from pathogenic microorganisms. [6, с. 3–4]. The scientific literature also considers the possibility of using antimicrobial agents of natural origin. Studies have shown that metabolites of the microalgae