Proceedings of the International scientific and practical conference ―Current Issues in Science‖ (January 9-11, 2026) / Publisher website: www.naukainfo.com. – Dresden, Germany, 2026. – 179 p.

60 Nail plate damage is not only a clinical manifestation of the disease, but also a marker of its more severe course, associated with a longer duration of the disease, higher activity of the inflammatory process, and a significant reduction in quality of life. Onychomycosis, in turn, is one of the most common infectious nail pathologies and accounts for up to 50% of all nail disorders. Its chronic course, tendency to recur and long-term treatment place a significant burden on the healthcare system. The combination of nail psoriasis and onychomycosis forms a separate group of patients with comorbid pathology, which goes beyond a purely clinical problem and becomes a public health issue [2]. From a public health perspective, the comorbidity of nail psoriasis and onychomycosis is multidimensional [3.4]: Firstly, both diseases are common among people of working age, leading to reduced professional activity, loss of working time and decreased economic productivity; Secondly, the chronic and recurrent course of the disease necessitates prolonged medical care, repeated consultations, laboratory tests and combination therapy, which increases the direct costs of the healthcare system; Thirdly, insufficient awareness of the possible combination of these pathologies contributes to diagnostic errors, irrational use of immunosuppressive drugs and prolonged treatment. For practising physicians, the problem of comorbidity of nail psoriasis and onychomycosis is particularly relevant in the context of the widespread use of systemic and biological therapy. Prescribing immunosuppressive drugs without first ruling out fungal nail infection can lead to progression of the infectious process, reduced treatment efficacy and therapeutic complications. That is why the detection of onychomycosis in patients with nail psoriasis is an important element of safe and rational clinical practice.