Proceedings of the International scientific and practical conference ―Synergy of Modern Science and Education‖ (February 2-4, 2026) / Publisher website: www.naukainfo.com. – New York, USA, 2026. - 324 p.

117 corpus luteum after ovulation [8]. Magnesium reduces cortisol levels, preventing the "stealing of pregnenolone" towards the synthesis of cortisol. In chronic stress, this mineral makes a more optimal ratio of pregnenolone and progesterone. Magnesium deficiency leads to muscle spasms, sleep disturbances. Iodine increases the sensitivity of progesterone receptors in the mammary glands. Prevents the development of progesterone resistance at normal levels [9]. Testosterone. Zinc acts as an inhibitor of the aromatase enzyme (CYP19A1), which prevents excessive conversion of testosterone to estradiol. Increases the sensitivity of the pituitary gland to GnRH, which optimizes the release of LH and the synthesis of testosterone in the theca cells of the ovaries [10]. Reduces the level of sex hormone binding globulin (SHBG), increasing the biologically active fraction of testosterone. Deficiency leads to an imbalance: a decrease in free testosterone and a relative increase in estrogens. Magnesium improves insulin sensitivity, reducing insulin-mediated stimulation of testosterone synthesis in PCOS. Reduces the level of cortisol - a competitive inhibitor of testosterone [11]. Selenium provides detoxification of excess hormones in the liver, contributing to the estrogen- testosterone balance. Protects ovarian cells from oxidative stress [12]. Prolactin. Zinc inhibits prolactin secretion in pituitary lactotrophs. Potentiates dopaminergic signaling - a physiological inhibitor of prolactin. Deficiency leads to: increased basal prolactin levels, suppression of GnRH pulsatility, impaired LH/FSH synthesis. Magnesium reduces the stress response through modulation of NMDA receptors and GABAergic systems [13]. Conclusion. The menstrual cycle is regulated by minerals, so minerals are extremely important for a person, especially for a woman, to have a regular and painless cycle. Excess or deficiency of minerals is dangerous for the regulation of the menstrual cycle, so women are advised to monitor their diet and dietary supplements to avoid further disturbances in regulation and sensitivity.